Clinical characteristics and genetic profiles of 174 patients with X-linked agammaglobulinemia
نویسندگان
چکیده
منابع مشابه
Clinical characteristics and genetic profiles of 174 patients with X-linked agammaglobulinemia
X-linked agammaglobulinemia (XLA) is a humoral primary immunodeficiency. XLA patients typically present with very low numbers of peripheral B cells and a profound deficiency of all immunoglobulin isotypes. Most XLA patients carry mutations in Bruton tyrosine kinase (BTK) gene.The genetic background and clinical features of 174 Chinese patients with XLA were investigated. The relationship betwee...
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ژورنال
عنوان ژورنال: Medicine
سال: 2016
ISSN: 0025-7974
DOI: 10.1097/md.0000000000004544